Delayed hypersensitivity at the injection sites of a low-molecular-weight heparin

被引：19

作者：

Moreau, A ^{[1
]}

Dompmartin, A ^{[1
]}

Esnault, P ^{[1
]}

Michel, M ^{[1
]}

Leroy, D ^{[1
]}

机构：

[1] DEPT DERMATOL,CAEN,FRANCE

来源：

CONTACT DERMATITIS | 1996年 / 34卷 / 01期

关键词：

heparin; delayed hypersensitivity; eczema; drug reaction; cutaneous side-effects; intradermal tests; subcutaneous tests; patch testing technique;

D O I：

10.1111/j.1600-0536.1996.tb02108.x

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 [免疫学];

摘要：

We report a case of delayed hypersensitivity to a low-molecular-weight heparin. The patient presented with eczema at the site of subcutaneous injections and allergy tests confirmed the clinical diagnosis. There were positive tests with 3 low-molecular-weight heparins and unfractionated subcutaneous calcium heparin but negative with intravenous sodium heparin. Although delayed hypersensitivity to low-molecular-weight heparins is rare, the possibility of cross-allergy to unfractionated heparin could be a therapeutic problem for some patients. (C) Munksgaard, 1996.

引用

页码：31 / 34

页数：4

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