The preparation and Wittig condensations of C-4 thiazole phosphonium methylides

被引：18

作者：

Williams, DR ^{[1
]}

Brooks, DA ^{[1
]}

Moore, JL ^{[1
]}

Stewart, AO ^{[1
]}

机构：

[1] ABBOTT LABS,ABBOTT PK,IL 60064

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 07期

基金：

美国国家卫生研究院;

关键词：

thiazole synthesis; phosphonium salts;

D O I：

10.1016/0040-4039(95)02358-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A modification of the Hantzsch thiazole synthesis is described which produces C-4 thiazolylmethyl phosphonium salts. Ylides are condensed with a variety of aldehydes to produce a series of 2,4-disubstituted thiazoles.

引用

页码：983 / 986

页数：4

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