Glucosides from Vitex agnus-castus

被引：70

作者：

Kuruüzüm-Uz, A

Ströch, K

Demirezer, LÖ

Zeeck, A

机构：

[1] Hacettepe Univ, Fac Pharm, Dept Pharmacognosy, TR-06100 Ankara, Turkey

[2] Univ Gottingen, Inst Organ Chem, D-37077 Gottingen, Germany

来源：

PHYTOCHEMISTRY | 2003年 / 63卷 / 08期

关键词：

Vitex agnus-castus; Verbenaceae; iridoid glucosides; aucubin; mussaenosidic acids; agnucastosides A-C; myzodendrone;

D O I：

10.1016/S0031-9422(03)00285-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

The methanolic extract of the flowering steins of Vitex agnus-castus yielded three new iridoids: 6'-O-foliamenthoylmussaenosidic acid (agnucastoside A), 6'-O-(6,7-dihydrofoliamenthoyl)mussaenosidic acid (agnucastoside B) and 7-O-trans-p-coumaroyl-6'-O-trans-caffeoyl-8-epiloganic acid (agnucastoside C) in addition to four known iridoids (aucubin, agnuside, mussaenosidic acid and 6'O-p-hydroxybenzoylmussaenosidic acid) and one known phenylbutanone glucoside (myzodendrone). The structure elucidations were mainly done by spectroscopic methods (1D and 2D NMR spectra) and MS data interpretation. The purified compounds were tested for biological activities against various microorganisms and cancer cell lilies. (C) 2003 Elsevier Ltd. All rights reserved.

引用

页码：959 / 964

页数：6

共 47 条

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CHEMISTRY OF THE SOROPHULARIACEAE .16. IRIDOID GLUCOSIDES OF PENSTEMON-AMBIGUUS [J].