Remarkable ligand effect on the enantioselectivity of the chiral lanthanum complex-catalyzed asymmetric epoxidation of enones

被引：88

作者：

Daikai, K ^{[1
]}

Kamaura, M ^{[1
]}

Inanaga, J ^{[1
]}

机构：

[1] Kyushu Univ, Inst Fundamental Res Organ Chem, Higashi Ku, Fukuoka 8128581, Japan

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 40期

关键词：

D O I：

10.1016/S0040-4039(98)01569-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The addition of triphenylphosphine oxide significantly enhanced the degree of asymmetric induction (up to 96% ee) in the chiral La-BINOL-complex-catalyzed epoxidation of enones using tert-butyl hydroperoxide as the oxidant. The new protocol is highly general and practical. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：7321 / 7322

页数：2

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