Remission of alcohol dependency following deep brain stimulation of the nucleus accumbens: valuable therapeutic implications?

被引：204

作者：

Kuhn, Jens

Lenartz, Doris

Huff, Wolfgang

Lee, SunHee

Koulousakis, Athanasios

Klosterkoetter, Joachim

Sturm, Volker

机构：

[1] Univ Cologne, Dept Psychiat & Psychotheraphy, D-50924 Cologne, Germany

[2] Univ Cologne, Dept Stereotaxy & Funct Neurosurg, Cologne, Germany

来源：

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY | 2007年 / 78卷 / 10期

关键词：

D O I：

10.1136/jnnp.2006.113092

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Chronic consumption of alcohol represents one of the greatest health and socioeconomic problems worldwide. We report on a 54- year- old patient with a severe anxiety disorder and secondary depressive disorder in whom bilateral deep brain stimulation ( DBS) of the nucleus accumbens was carried out. Despite the absence of desired improvement in his primary disorder, we observed a remarkable although not primarily intended alleviation of the patient's comorbid alcohol dependency. Our case report demonstrates the extremely effective treatment of alcohol dependency by means of DBS of the nucleus accumbens and may reveal new prospects in overcoming therapy resistance in dependencies in general.

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页码：1152 / 1153

页数：2

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