Treatment of chronic osteomyelitis using calcium hydroxyapatite ceramic implants impregnated with antibiotic

被引：92

作者：

Yamashita, Y ^{[1
]}

Uchida, A ^{[1
]}

Yamakawa, T ^{[1
]}

Shinto, Y ^{[1
]}

Araki, N ^{[1
]}

Kato, K ^{[1
]}

机构：

[1] Mie Univ, Fac Med, Dept Orthopaed Surg, Tsu, Mie 514, Japan

来源：

INTERNATIONAL ORTHOPAEDICS | 1998年 / 22卷 / 04期

关键词：

D O I：

10.1007/s002640050252

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

We treated eighteen patients with chronic osteomyelitis by implanting pieces of antibiotic-impregnated calcium hydroxyapatite ceramic into a cavity produced after thorough surgical excision of necrotic tissue. Within three months the infected sites had ail healed. During follow-trp ranging from 24 to 75 months there was no recurrence of infection. Two of the patients had infected prosthetic joints which were successfully revised. Infection was controlled and incorporation of the ceramic material into host bone was demonstrated radiographically. We recommend the use of porous pieces of calcium hydroxyapatite impregnated with antibiotic as a new system for drug delivery in the treatment of chronic osteomyelitis.

引用

页码：247 / 251

页数：5

共 16 条

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