Dietary patterns and the metabolic syndrome in obese and non-obese Framingham women

被引:78
作者
Sonnenberg, L
Pencina, M
Kimokoti, R
Quatromoni, P
Nam, BH
D'Agostino, R
Meigs, JB
Ordovas, J
Cobain, M
Millen, B
机构
[1] Boston Univ, Sch Publ Hlth, Dept Social & Behav Sci, Boston, MA 02118 USA
[2] Massachusetts Gen Hosp, Dept Nutr & Food Serv, Ambulatory Nutr Serv, Boston, MA 02114 USA
[3] Boston Univ, Dept Math, Boston, MA 02215 USA
[4] Sargent Coll Hlth & Rehabil Sci, Dept Hlth Sci, Boston, MA USA
[5] Massachusetts Gen Hosp, Dept Med, Div Gen Internal Med, Boston, MA 02114 USA
[6] Harvard Univ, Sch Med, Boston, MA USA
[7] Tufts Univ, Sch Med, Lipid Metab Lab, USDA,Human Nurt Res Ctr Aging, Boston, MA 02111 USA
[8] Boston Univ, Sch Med, Grad Med Sci Div, Boston, MA 02118 USA
[9] Boston Univ, Sch Med, Dept Sociomed Sci, Boston, MA 02118 USA
来源
OBESITY RESEARCH | 2005年 / 13卷 / 01期
关键词
dietary patterns; risk factor; diabetes; genetic phenotype; cardiovascular disease;
D O I
10.1038/oby.2005.20
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objectives: To examine the relationship between habitual dietary patterns and the metabolic syndrome (MetS) in women and to identify foci for preventive nutrition interventions. Research Methods and Procedures: Dietary patterns, nutrient intake, cardiovascular disease (CVD), and MetS risk factors were characterized in 1615 Framingham Offspring-Spouse Study (FOS) women. Dietary pattern subgroups were compared for MetS prevalence and CVD risk factor status using logistic regression and analysis of covariance. Analyses were performed overall in women and stratified on obesity status; multivariate models controlled for age, apolipoprotein E (APOE) genotypes, and CVD risk factors. Results: Food and nutrient profiles and overall nutritional risk of five non-overlapping habitual dietary patterns of women were identified including Heart Healthier, Lighter Eating, Wine and Moderate Eating, Higher Fat, and Empty Calories. Rates of hypertension and low high-density lipoprotein levels were high in non-obese women, but individual MetS risk factor levels were substantially increased in obese women. Overall MetS risk varied by dietary pattern and obesity status, independently of APOE and CVD risk factors. Compared with obese or non-obese women and women overall with other dietary patterns, MetS was highest in those with the Empty Calorie pattern (contrast p value: p < 0.05). Discussion: This research shows the independent relationship between habitual dietary patterns and MetS risk in FOS women and the influence of obesity status. High overall MetS risk and the varying prevalence of individual MetS risk factors in female subgroups emphasize the importance of preventive nutrition interventions and suggest potential benefits of targeted behavior change in both obese and non-obese women by dietary pattern.
引用
收藏
页码:153 / 162
页数:10
相关论文
共 46 条
[1]  
*AM DIAB ASS AM DI, 1989, EXCH LISTS MEAL PLAN
[2]  
*AM DIET ASS, 1981, HDB CLIN DIET
[3]  
Austin MA, 1996, AM J EPIDEMIOL, V144, P437
[4]   The National Cholesterol Education Program - Progress and prospects [J].
Cleeman, JI ;
Lenfant, C .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1998, 280 (24) :2099-2104
[5]   Executive summary of the Third Report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III) [J].
Cleeman, JI ;
Grundy, SM ;
Becker, D ;
Clark, LT ;
Cooper, RS ;
Denke, MA ;
Howard, WJ ;
Hunninghake, DB ;
Illingworth, DR ;
Luepker, RV ;
McBride, P ;
McKenney, JM ;
Pasternak, RC ;
Stone, NJ ;
Van Horn, L ;
Brewer, HB ;
Ernst, ND ;
Gordon, D ;
Levy, D ;
Rifkind, B ;
Rossouw, JE ;
Savage, P ;
Haffner, SM ;
Orloff, DG ;
Proschan, MA ;
Schwartz, JS ;
Sempos, CT ;
Shero, ST ;
Murray, EZ .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2001, 285 (19) :2486-2497
[6]  
CUPPLES LA, 1987, NIH PUBLICATIONS
[7]  
D'Agostino R.B., 1989, P AM STAT ASS SESQUI, P707
[8]  
Dawber ThomasR., 1980, FRAMINGHAM STUDY EPI
[9]   Apolipoprotein E polymorphism and cardiovascular disease: A HuGE review [J].
Eichner, JE ;
Dunn, ST ;
Perveen, G ;
Thompson, DM ;
Stewart, KE ;
Stroehla, BC .
AMERICAN JOURNAL OF EPIDEMIOLOGY, 2002, 155 (06) :487-495
[10]   Prevalence and trends in obesity among US adults, 1999-2000 [J].
Flegal, KM ;
Carroll, MD ;
Ogden, CL ;
Johnson, CL .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2002, 288 (14) :1723-1727