Preparation and characterization of water-soluble chitin and chitosan derivatives

被引：364

作者：

Sugimoto, M

Morimoto, M

Sashiwa, H

Saimoto, H

Shigemasa, Y ^{[1
]}

机构：

[1] Tottori Univ, Fac Engn, Dept Mat Sci, Tottori 680, Japan

[2] Nippon NSC Ltd, Osaka 562, Japan

来源：

CARBOHYDRATE POLYMERS | 1998年 / 36卷 / 01期

关键词：

chitin; chitosan derivatives; PEG-aldehyde;

D O I：

10.1016/S0144-8617(97)00235-X

中图分类号：

O69 [应用化学];

学科分类号：

081704 [应用化学];

摘要：

Chitosan was modified with poly(ethylene glycol)-aldehyde (PEG-aldehyde) of various molecular weights under the various molar ratios of PEG-aldehyde to chitosan. Then the prepared chitosan-PEG hybrid was converted to chitin-PEG hybrid by the acetylation with acetic anhydride. The solubility of various derivatives was investigated in three buffers of various pH. Some of these derivatives were soluble in 0.01 M phosphate buffer saline (PBS, pH = 7.2). The solubility in PBS was dependent on the degree of PEG substitution, the degree of acetylation, the molecular weight of PEG, and the weight ratio of PEG in chitin/chitosan-PEG hybrid. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：49 / 59

页数：11

共 23 条

[1]

STUDIES ON CHITOSAN .2. SOLUTION STABILITY AND REACTIVITY OF PARTIALLY N-ACETYLATED CHITOSAN DERIVATIVES IN AQUEOUS-MEDIA [J].