Regioselective synthesis of several heterocyclic fused azepines using diisobutylaluminum hydride

被引：27

作者：

Cho, H ^{[1
]}

Murakami, K ^{[1
]}

Nakanishi, H ^{[1
]}

Isoshima, H ^{[1
]}

Hayakawa, K ^{[1
]}

Uchida, I ^{[1
]}

机构：

[1] Japan Tobacco Inc, Cent Pharmaceut Res Inst, Takatsuki, Osaka 5691125, Japan

来源：

HETEROCYCLES | 1998年 / 48卷 / 05期

关键词：

D O I：

10.3987/COM-98-8104

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

5,6,7,8-Tetrahydrothieno[3,2-b]azepine,5,6,7,8-tetrahydro-1H-furo[3,- 2b]azepine, and 1,4,5,6,7,8-hexahydropyrrolo [3,2-b]azepine were synthesized by the ring expansion reaction of heterocyclic fused cyclohexanone oximes with diisobutylaluminum hydride (DIBAH). The mechanism of the reaction was different from that of Beckmann rearrangement.

引用

页码：919 / 927

页数：9

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