Improved selectivity and stability of glucose biosensor based on in situ electropolymerized polyaniline-polyacrylonitrile composite film

被引：58

作者：

Xue, HG ^{[1
]}

Shen, ZQ

Li, CM

机构：

[1] Yangzhou Univ, Sch Chem & Chem Engn, Yangzhou 225002, Peoples R China

[2] Zhejiang Univ, Inst Polymer Sci, Hangzhou 310027, Peoples R China

来源：

BIOSENSORS & BIOELECTRONICS | 2005年 / 20卷 / 11期

基金：

中国国家自然科学基金;

关键词：

glucose biosensor; in situ electropolymerization; polyaniline-polyacrylonitrile composites; selectivity; stability;

D O I：

10.1016/j.bios.2004.07.018

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

A new type of in situ electropolymerization method was used for electrochemical biosensor design. The biologic film was prepared by in situ electropolymerization of aniline into microporous polyacrylonitrile-coated platinum electrode in the presence of glucose oxidase. The novel glucose biosensor exhibited good selectivity, sensitivity and stability, which showed no apparent loss of activity after 100 consecutive measurements and intermittent usage for 100 days with storage in a phosphate buffer at 4 degrees C. Blood glucose determinations agreed well with standard hospital laboratory analysis. The construction and operational parameters of the biosensor were also optimized. (c) 2004 Elsevier B.V. All rights reserved.

引用

页码：2330 / 2334

页数：5

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