The evolution of biotransformation technologies

被引:37
作者
Dordick, JS [1 ]
Khmelnitsky, YL
Sergeeva, MV
机构
[1] Univ Iowa, Dept Chem & Biochem Engn, Iowa City, IA 52242 USA
[2] Univ Iowa, Div Med & Nat Prod Chem, Iowa City, IA 52242 USA
[3] EnzyMed Inc, Iowa City, IA 52242 USA
关键词
D O I
10.1016/S1369-5274(98)80035-0
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Biotransformation is a broad and growing field of biotechnology and encompasses both enzymatic and microbial biocatalysis. Progress has been made in research on the key drivers of biotransformations, including the isolation and characterization of microbes and their enzymes from, and their utilization in, extreme environments, the manipulation, alteration, and augmentation of metabolic pathways, and the use of combinatorial biosynthesis and biocatalytic methodologies for new compound development.
引用
收藏
页码:311 / 318
页数:8
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