Comparative pathology of the diseases caused hy Hendra and Nipah viruses

被引:151
作者
Hooper, P
Zaki, S
Daniels, P
Middleton, D
机构
[1] CSIRO, Australian Anim Hlth Lab, Geelong, Vic 3220, Australia
[2] Ctr Dis Control & Prevent, Div Med Ecol, Natl Ctr Infect Dis, Atlanta, GA 30333 USA
关键词
pathogenesis; transmissibility; pathology; vasotropism; neurotropism; Hendra virus; Nipah virus;
D O I
10.1016/S1286-4579(01)01385-5
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Information on the pathogenesis and transmissibility of Hendra and Nipah viruses was obtained by comparing their histopathology. Both viruses induced syncytial cells in vascular tissues and they were primarily vasotropic and/or neurotropic, generating interstitial pneumonia or encephalitis. Nipah virus in Digs was also epitheliotropic in respiratory epithelium and thus contagious. (C) 2001 Editions scientifiques et medicales Elsevier SAS.
引用
收藏
页码:315 / 322
页数:8
相关论文
共 17 条
[1]   Fatal encephalitis due to Nipah virus among pig-farmers in Malaysia [J].
Chua, KB ;
Goh, KJ ;
Wong, KT ;
Kamarulzaman, A ;
Tan, PSK ;
Ksiazek, TG ;
Zaki, SR ;
Paul, G ;
Lam, SK ;
Tan, CT .
LANCET, 1999, 354 (9186) :1257-1259
[2]   Newly discovered viruses of flying foxes [J].
Halpin, K ;
Young, PL ;
Field, H ;
Mackenzie, JS .
VETERINARY MICROBIOLOGY, 1999, 68 (1-2) :83-87
[3]   Lesions of experimental equine morbillivirus pneumonia in horses [J].
Hooper, PT ;
Ketterer, PJ ;
Hyatt, AD ;
Russell, GM .
VETERINARY PATHOLOGY, 1997, 34 (04) :312-322
[4]   The lesions of experimental equine morbillivirus disease in cats and guinea pigs [J].
Hooper, PT ;
Westbury, HA ;
Russell, GM .
VETERINARY PATHOLOGY, 1997, 34 (04) :323-329
[5]   Ultrastructure of equine morbillivirus [J].
Hyatt, AD ;
Selleck, PW .
VIRUS RESEARCH, 1996, 43 (01) :1-15
[6]  
KARIM N, 1999, P SEM NIP VIR NAT C, P3
[7]   Transmissibility from horses to humans of a novel paramyxovirus, equine morbillivirus (EMV) [J].
McCormack, JG ;
Allworth, AM ;
Selvey, LA ;
Selleck, PW .
JOURNAL OF INFECTION, 1999, 38 (01) :22-23
[8]  
MIDDLETON D, 1999, 12 INT C VIR SYDN AU, P39
[9]   A MORBILLIVIRUS THAT CAUSED FATAL DISEASE IN HORSES AND HUMANS [J].
MURRAY, K ;
SELLECK, P ;
HOOPER, P ;
HYATT, A ;
GOULD, A ;
GLEESON, L ;
WESTBURY, H ;
HILEY, L ;
SELVEY, L ;
RODWELL, B ;
KETTERER, P .
SCIENCE, 1995, 268 (5207) :94-97
[10]   Fatal encephalitis due to novel paramyxovirus transmitted from horses [J].
OSullivan, JD ;
Allworth, AM ;
Paterson, DL ;
Snow, TM ;
Boots, R ;
Gleeson, LJ ;
Gould, AR ;
Hyatt, AD ;
Bradfield, J .
LANCET, 1997, 349 (9045) :93-95