Facile synthesis of symmetrical functionalized biaryls from aryl halides catalyzed by commercial zinc dust using ammonium formate

被引：39

作者：

Abiraj, K ^{[1
]}

Srinivasa, GR ^{[1
]}

Gowda, DC ^{[1
]}

机构：

[1] Univ Mysore, Dept Studies Chem, Mysore 570006, Karnataka, India

来源：

TETRAHEDRON LETTERS | 2004年 / 45卷 / 10期

关键词：

aryl halides; homocoupling; zinc; ammonium formate; biaryls;

D O I：

10.1016/j.tetlet.2004.01.076

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Reductive homocoupling of aryl halides in the presence of commercial zinc dust and ammonium formate in methanol produces biaryls in good to excellent yields. Aryl halides having either electron-donating or electron-withdrawing groups underwent smooth coupling to afford the corresponding symmetrical biaryls. Addition of 1 equiv of sodium hydroxide enhanced the coupling reaction rate. Commercial zinc dust is inexpensive, widely available and can be used without any auxiliary catalysts such as Pd(0) and/or Ni(0). (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：2081 / 2084

页数：4

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