Rapid detection of a common dihydropyrimidine dehydrogenase mutation associated with 5-fluorouracil toxicity and congenital thymine uraciluria using fluorogenic hybridization probes

被引：15

作者：

Nauck, M ^{[1
]}

Gierens, H ^{[1
]}

März, W ^{[1
]}

Wieland, H ^{[1
]}

机构：

[1] Univ Hosp Freiburg, Dept Clin Chem, D-79106 Freiburg, Germany

来源：

CLINICAL BIOCHEMISTRY | 2001年 / 34卷 / 02期

关键词：

pharmacogenetics; thymine-uraciluaria; 5-fluorouracil toxicity; genotyping PCR; hybridization probes; fluorescence resonance energy transfer;

D O I：

10.1016/S0009-9120(01)00188-6

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

[No abstract available]

引用

页码：103 / 105

页数：3

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