Synthesis of DL-isocysteine and some derivatives from thiomalic acid

被引：12

作者：

Pires, R ^{[1
]}

Burger, K ^{[1
]}

机构：

[1] UNIV LEIPZIG,INST ORGAN CHEM,D-04103 LEIPZIG,GERMANY

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 45期

关键词：

D O I：

10.1016/0040-4039(96)01837-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Thiomalic acid is transformed into isocysteine using hexafluoroacetone as protecting and activating agent. The urethanes 5, 6, 7 obtained represent N-protected, carboxylic group activated derivatives of isocysteine and are perfectly suited for further derivatizations. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：8159 / 8160

页数：2

共 8 条

[1]

FOTOUHI N, 1994, J BIOL CHEM, V269, P30227

[2]

GANTE J, 1994, ANGEW CHEM INT EDIT, V33, P1699, DOI 10.1002/anie.199416991

[3] PEPTIDOMIMETICS FOR RECEPTOR LIGANDS DISCOVERY, DEVELOPMENT, AND MEDICAL PERSPECTIVES [J].