Is PBEF/visfatin/Nampt an authentic adipokine relevant to the metabolic syndrome?

被引：46

作者：

Sethi, Jaswinder K. ^{[1
]}

机构：

[1] Univ Cambridge, Addenbrookes Hosp, Dept Clin Biochem, Cambridge CB2 2QR, England

来源：

CURRENT HYPERTENSION REPORTS | 2007年 / 9卷 / 01期

基金：

英国生物技术与生命科学研究理事会;

关键词：

D O I：

10.1007/s11906-007-0007-5

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

Adipokines are peptides secreted by adipose tissue that affect whole-body energy metabolism. Their dysregulated production in obesity has implicated them as important mediators in the pathogenesis of obesity-related risk factors for diabetes and cardiovascular disease. PBEF/visfatin/Nampt has recently been described as a novel adipokine with insulin mimetic properties. However, whether it is an authentic adipokine relevant to the metabolic syndrome remains a matter of some debate.

引用

页码：33 / 38

页数：6

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