Why does smoking so often produce dependence? A somewhat different view

被引:25
作者
Hughes, JR [1 ]
机构
[1] Univ Vermont, Dept Psychiat, Burlington, VT 05401 USA
关键词
nicotine; substance use disorder; substance withdrawal; tobacco use disorder;
D O I
10.1136/tc.10.1.62
中图分类号
R194 [卫生标准、卫生检查、医药管理];
学科分类号
摘要
The usual explanation for why smoking produces dependence focuses on the effects of nicotine on dopamine and other neurobiological explanations. This review offers four somewhat different explanations: (1) nicotine can offer several psychopharmacological benefits at the age when such benefits are especially needed; (2) cigarettes provide for a rapid, frequent, reliable and easy-to-obtain reward; (3) nicotine is not intoxicating, allowing chronic intake; and (4) the long duration of the nicotine withdrawal syndrome effectively undermines cessation. This article reviews the evidence for the above views and the tobacco control activities these views suggest.
引用
收藏
页码:62 / 64
页数:3
相关论文
共 28 条
[1]   Comparative Epidemiology of Dependence on Tobacco, Alcohol, Controlled Substances, and Inhalants: Basic Findings From the National Comorbidity Survey [J].
Anthony, James C. ;
Warner, Lynn A. ;
Kessler, Ronald C. .
EXPERIMENTAL AND CLINICAL PSYCHOPHARMACOLOGY, 1994, 2 (03) :244-268
[2]  
BENOWITZ NL, 1988, DHHS PUBLICATION, P377
[3]  
BRECHER EM, 1972, LICIT ILLICIT DRUGS, P220
[4]   DSM-III-R NICOTINE DEPENDENCE IN YOUNG-ADULTS - PREVALENCE, CORRELATES AND ASSOCIATED PSYCHIATRIC-DISORDERS [J].
BRESLAU, N ;
KILBEY, MM ;
ANDRESKI, P .
ADDICTION, 1994, 89 (06) :743-754
[5]  
Colby SM, 2000, DRUG ALCOHOL DEPEN, V59, pS23
[6]  
Heishman SJ, 1998, ADDICTION, V93, P317
[7]  
HUGHES JR, 1990, RES ADV ALCOHOL DRUG, V10, P317
[8]   DISTINGUISHING WITHDRAWAL RELIEF AND DIRECT EFFECTS OF SMOKING [J].
HUGHES, JR .
PSYCHOPHARMACOLOGY, 1991, 104 (03) :409-410
[9]   TOBACCO WITHDRAWAL IN SELF-QUITTERS [J].
HUGHES, JR .
JOURNAL OF CONSULTING AND CLINICAL PSYCHOLOGY, 1992, 60 (05) :689-697
[10]   Prevalence and demographic correlates of symptoms of last year dependence on alcohol, nicotine, marijuana and cocaine in the US population [J].
Kandel, D ;
Chen, K ;
Warner, LA ;
Kessler, RC ;
Grant, B .
DRUG AND ALCOHOL DEPENDENCE, 1997, 44 (01) :11-29