Biomimetic Synthesis of Dendridine A

被引：24

作者：

Boyd, Emily M. ^{[1
]}

Sperry, Jonathan ^{[1
]}

机构：

[1] Univ Auckland, Sch Chem Sci, Auckland 1, New Zealand

来源：

ORGANIC LETTERS | 2015年 / 17卷 / 05期

关键词：

L. OIL CAKE; INDOLE ALKALOIDS; AROMATIC NUCLEI; OXIDATION; P-(+)-DISPEGATRINE; CHEMISTRY; PHENOLS; MOCL5;

D O I：

10.1021/acs.orglett.5b00300

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Biomimetic synthesis of the bisindole natural product dendridine A is reported. Although attempts to install the hindered biaryl bond by oxidative phenolic coupling of the 7-hydroxytryptamine 6 gave the undesired ortho-ortho product, a Scholl-type oxidative coupling of the 7-isopropoxytryptamine 9 with molybdenum pentachloride proceeded through the desired para-para pathway, installing the entire carbon framework of dendridine A.

引用

页码：1344 / 1346

页数：3

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