The principles of quantification applied to in vivo proton MR spectroscopy

被引：50

作者：

Helms, Gunther ^{[1
]}

机构：

[1] Univ Gottingen, Fac Med, D-37075 Gottingen, Germany

来源：

EUROPEAN JOURNAL OF RADIOLOGY | 2008年 / 67卷 / 02期

关键词：

MRS; brain; quantification; QA;

D O I：

10.1016/j.ejrad.2008.02.034

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Following the identification of metabolite signals in the in vivo MR spectrum, quantification is the procedure to estimate numerical values of their concentrations. The two essential steps are discussed in detail: analysis by fitting a model of prior knowledge, that is, the decomposition of the spectrum into the signals of singular metabolites; then, normalization of these signals to yield concentration estimates. Special attention is given to using the in vivo water signal as internal reference. (C) 2008 Elsevier Ireland Ltd. All rights reserved.

引用

页码：218 / 229

页数：12

共 23 条

[1] ABSOLUTE QUANTITATIVE PROTON NMR-SPECTROSCOPY BASED ON THE AMPLITUDE OF THE LOCAL WATER SUPPRESSION PULSE - QUANTIFICATION OF BRAIN WATER AND METABOLITES [J].