Synthesis of heparin oligosaccharides

被引：134

作者：

Lee, JC

Lu, XA

Kulkarni, SS

Wen, YS

Hung, SC ^{[1
]}

机构：

[1] Acad Sinica, Inst Chem, Taipei 115, Taiwan

[2] Natl Tsing Hua Univ, Dept Chem, Hsinchu 300, Taiwan

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2004年 / 126卷 / 02期

关键词：

D O I：

10.1021/ja038244h

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An efficient preparation of rare 2-O-benzoyl-3-O-benzyl-1,6-anhydro-β-l-idopyranose from commercially available diacetone α-d-glucose in five straightforward steps is described here. With this key building block in hand, the total syntheses of heparin oligosaccharides with three, five, seven, and nine sugar units are successfully carried out. Copyright © 2004 American Chemical Society.

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页码：476 / 477

页数：2

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