Alterations in GyrA and ParC associated with fluoroquinolone resistance in Enterococcus faecium

被引：51

作者：

El Amin, N ^{[1
]}

Jalal, S ^{[1
]}

Wretlind, B ^{[1
]}

机构：

[1] Huddinge Univ Hosp, Div Clin & Oral Bacteriol, Dept Immunol Microbiol Pathol & Infect Dis, S-14186 Huddinge, Sweden

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1999年 / 43卷 / 04期

关键词：

D O I：

10.1128/AAC.43.4.947

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

High-level quinolone resistance in Enterococcus faecium was associated with mutations in both gyrA and parC genes in 10 of 11 resistant strains. One low-level resistant strain without such mutations may instead possess an efflux mechanism or alterations in the other subunits of the gyrase or topoisomerase IV genes. These findings are similar to those for other gram-positive bacteria, such as Enterococcus faecalis.

引用

页码：947 / 949

页数：3

共 31 条

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