Use of liquid chromatography mass spectrometry in the analysis of residues of antibiotics in meat and milk

被引:128
作者
Kennedy, DG [1 ]
McCracken, RJ [1 ]
Cannavan, A [1 ]
Hewitt, SA [1 ]
机构
[1] Dept Agr No Ireland, Vet Sci Div, Belfast BT4 3SD, Antrim, North Ireland
关键词
reviews; antibiotics;
D O I
10.1016/S0021-9673(98)00048-X
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
The advent of affordable LC-MS systems has led to a massive increase in the number of publications describing quantitative methods for the analysis and confirmation of veterinary drug residues. The lack of volatility and thermal instability of many antibiotics makes LC-MS the method of choice for their analysis. In this review, analytical methods for the determination of residues of each of the major classes of antibiotics are presented. (C) 1998 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:77 / 98
页数:22
相关论文
共 53 条
[1]   HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY THERMOSPRAY MASS-SPECTROMETRY OF 10 SULFONAMIDE ANTIBIOTICS - ANALYSIS IN MILK AT THE PPB LEVEL [J].
ABIAN, J ;
CHURCHWELL, MI ;
KORFMACHER, WA .
JOURNAL OF CHROMATOGRAPHY, 1993, 629 (02) :267-276
[2]   COMPARISON OF THE DETERMINATION OF 4 SULFONAMIDES AND THEIR N-4-ACETYL METABOLITES IN SWINE MUSCLE-TISSUE USING LIQUID-CHROMATOGRAPHY WITH ULTRAVIOLET AND MASS-SPECTRAL DETECTION [J].
BALIZS, G ;
BENESCHGIRKE, L ;
BORNER, S ;
HEWITT, SA .
JOURNAL OF CHROMATOGRAPHY B-BIOMEDICAL APPLICATIONS, 1994, 661 (01) :75-84
[3]   CONFIRMATORY ASSAY FOR THE SIMULTANEOUS DETECTION OF 5 PENICILLINS IN MUSCLE, KIDNEY AND MILK USING LIQUID-CHROMATOGRAPHY - ELECTROSPRAY MASS-SPECTROMETRY [J].
BLANCHFLOWER, WJ ;
HEWITT, SA ;
KENNEDY, DG .
ANALYST, 1994, 119 (12) :2595-2601
[4]  
Blanchflower WJ, 1997, J CHROMATOGR B, V692, P351
[5]  
BLANCHFLOWER WJ, 1993, EURORESIDUE, V2, P196
[6]  
BOISON JO, 1995, J AOAC INT, V78, P651
[7]  
BOISON JOK, 1994, J AOAC INT, V77, P565
[8]   Determination of dimetridazole in poultry tissues and eggs using liquid chromatography thermospray mass spectrometry [J].
Cannavan, A ;
Kennedy, DG .
ANALYST, 1997, 122 (09) :963-966
[9]  
Commission Decision 93/256/EEC, 1993, OFF J EUR COMMUN L, VL118, P64
[10]  
Council Regulation (EEC), 1990, Official Journal of the European Communities L. Ser, V224, P1