The serotonin syndrome

被引：1049

作者：

Boyer, EW

Shannon, M

机构：

[1] Childrens Hosp, Div Emergency Med, Program Med Toxicol, Boston, MA 02115 USA

[2] Univ Massachusetts, Dept Emergency Med, Div Med Toxicol, Worcester, MA 01605 USA

来源：

NEW ENGLAND JOURNAL OF MEDICINE | 2005年 / 352卷 / 11期

关键词：

D O I：

10.1056/NEJMra041867

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The serotonin syndrome is a potentially life-threatening drug reaction that may result from therapeutic medication use, self-poisoning, or interactions between drugs. This review explains the clinical presentations that should lead to the diagnosis, the mechanisms of toxicity, and the drugs and interactions most often implicated. Clinical management includes measures to control agitation, autonomic instability, and hyperthermia.

引用

页码：1112 / 1120

页数：9

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