Chromium-mediated β-lactone synthesis using ultrasonication

被引：10

作者：

Caldwell, JJ

Harrity, JPA

Heron, NM

Kerr, WJ

McKendry, S

Middlemiss, D

机构：

[1] Univ Strathclyde, Dept Pure & Appl Chem, Glasgow G1 1XL, Lanark, Scotland

[2] Glaxo Wellcome, Med Res Ctr, Stevenage SG1 2NY, Herts, England

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 17期

关键词：

alkynes; chromium and compounds; lactones; sonochemistry;

D O I：

10.1016/S0040-4039(99)00429-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reaction of chromium aryl(alkoxy)carbenes with propargylic alcohols has been investigated under dry state adsorption and ultrasound conditions. When compared to the corresponding thermal processes, the developed sonication reactions afford good yields of p-lactone products over generally shorter reaction times. hy state adsorption affords diene products which are also obtained from the corresponding p-lactones. (C) 1999 Elsevier Science Ltd. All rights reserved.

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收藏

页码：3481 / 3484

页数：4

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