Flexible sigmoidoscopy screening for colorectal cancer in average-risk subjects: A community-based pilot project

被引:50
作者
Olynyk, JK
Aquilia, S
Fletcher, DR
Dickinson, JA
机构
[1] FREMANTLE HOSP,DEPT GASTROENTEROL,FREMANTLE,WA 6160,AUSTRALIA
[2] FREMANTLE HOSP,UNIV DEPT SURG,FREMANTLE,WA 6160,AUSTRALIA
[3] FREMANTLE HOSP,UNIV DEPT GEN PRACTICE,FREMANTLE,WA 6160,AUSTRALIA
关键词
D O I
10.5694/j.1326-5377.1996.tb124851.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objective: To test a pilot screening program for colorectal cancer. Design: Subjects, chosen at random and recruited by mail, were examined by flexible sigmoidoscopy. Participants and setting: Normal-risk, asymptomatic men and women aged 55-59 years recruited from the community, July to December, 1995. Main outcome measures: Number of polyps detected and cancers diagnosed, and compliance with screening. Results: Letters of invitation were sent to 3500 subjects; of these, 2881 were eligible for inclusion in the study and 342 (12%) consented to participate. A further 3.5% of non-compliant subjects attended the screening program after a telephone survey assessing reasons for non-attendance. Common reasons for non-attendance were a lack of interest (30%) or a lack of time, mainly due to work commitments (28%). A third of subjects had polyps and 46% of these were adenomas. Three subjects were found to have adenocarcinoma: in two the cancer was confined to a polyp and treated with polypectomy, and one subject underwent anterior resection (overall prevalence oi cancer, 0.9%). The median depth of insertion achieved with flexible sigmoidoscopy was 55 cm (range, 25-100 cm). Median pain level (on a scale or 0=no pain to 10=worst pain imaginable) was 2 (range, 0-8.5), and 99% of the subjects would have the test again if required. Conclusions: Flexible sigmoidoscopy was well tolerated and had an acceptable detection rate of adenomatous polyps and early cancer. Subject compliance emerged as a major issue which requires further evaluation to maximise participation in future programs.
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页码:74 / 76
页数:3
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