Multifunctional nanoparticles possessing a "magnetic motor effect" for drug or gene delivery

被引:359
作者
Yoon, TJ
Kim, JS
Kim, BG
Yu, KN
Cho, MH [1 ]
Lee, JK
机构
[1] Seoul Natl Univ, Sch Chem, Mat Chem Lab, Seoul 151747, South Korea
[2] Seoul Natl Univ, Coll Vet Med, Lab Toxicol, Seoul 151747, South Korea
[3] Seoul Natl Univ, Sch Agr Biotechnol, Seoul 151747, South Korea
关键词
bioinorganic chemistry; fluorescent probes; hybrid materials; magnetic properties; nanotechnology;
D O I
10.1002/anie.200461910
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Cells in motion: Multifunctional nanoparticles, with a unique combination of magnetic and fluorescent properties, coupled with biocompatibility are prepared. The uptake of the magnetic nanoparticles by cells is investigated, and an external "magnetic motor effect" on the cells containing the nanoparticles is observed (see scheme). © 2005 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码:1068 / 1071
页数:4
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