Transformation of essential thrombocythaemia to T cell acute lymphoblastic leukaemia

被引:7
作者
Berkahn, LC [1 ]
Nelson, J [1 ]
Ockelford, PA [1 ]
Browett, PJ [1 ]
机构
[1] UNIV AUCKLAND,AUCKLAND HOSP,DEPT HAEMATOL,AUCKLAND,NEW ZEALAND
关键词
essential thrombocythaemia; T cell acute lymphoblastic leukaemia;
D O I
10.3109/10428199609051630
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Leukaemic transformation of essential thrombocythaemia is a rare event and is usually associated with previous treatment with either alkylating agents or radioactive phosphorous. We describe a patient with essential thrombocythaemia who developed an acute leukaemia of T cell phenotype following hydroxyurea therapy. The T cell phenotype of the blasts suggests the tar et cell for leukaemic a transformation was a pluripotential stem cell.
引用
收藏
页码:347 / 349
页数:3
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