Quorum sensing in Acinetobacter: an emerging pathogen

被引：144

作者：

Bhargava, Nidhi ^{[1
]}

Sharma, Prince ^{[2
]}

Capalash, Neena ^{[1
]}

机构：

[1] Panjab Univ, Dept Biotechnol, Chandigarh 160014, India

[2] Panjab Univ, Dept Microbiol, Chandigarh 160014, India

来源：

CRITICAL REVIEWS IN MICROBIOLOGY | 2010年 / 36卷 / 04期

关键词：

TO-CELL COMMUNICATION; BIOFILM FORMATION; ANTIBACTERIAL ACTIVITY; BAUMANNII INFECTION; CRYSTAL-STRUCTURE; ESCHERICHIA-COLI; MEDICINAL-PLANTS; ABIOTIC SURFACES; VIBRIO-FISCHERI; BACTERIAL;

D O I：

10.3109/1040841X.2010.512269

中图分类号：

Q93 [微生物学];

学科分类号：

071005 [微生物学];

摘要：

Acinetobacter is emerging as one of the major nosocomial infectious pathogens, facilitated by tolerance to desiccation and multidrug resistance. Quorum sensing (autoinducer-receptor mechanism) plays role in biofilm formation in Acinetobacter, though its role in regulation of other virulence factors is yet to be established. Phylogenetic studies indicate that Acinetobacter baumannii is closely related to Burkholderia ambifaria but its quorum sensing genes (abaI and abaR) were acquired horizontally from Halothiobacillus neapolitanus. The prospects of quorum quenching to control the infections caused by Acinetobacter have also been discussed.</.

引用

页码：349 / 360

页数：12

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