Intraoral salivary duct carcinoma: Case report with immunohistochemical observations

被引：6

作者：

Lopes, MA

Alves, FD

Levy, BA

de Almeida, OP

Kowalski, LP

机构：

[1] Univ Estadual Campinas, Fac Odontol Piracicaba, Dept Diagnost Oral, Sch Dent Piracicaba, BR-13414018 Sao Paulo, Brazil

[2] Univ Maryland, Sch Dent, Baltimore, MD 21201 USA

来源：

ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTOLOGY | 2001年 / 91卷 / 06期

基金：

巴西圣保罗研究基金会;

关键词：

D O I：

10.1067/moe.2001.115028

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

Salivary duct carcinoma is an uncommon malignant salivary gland tumor that occurs predominantly in the parotid gland. Oral involvement is extremely rare, with few cases having been reported in the literature. The tumor is characterized by an aggressive behavior and has a poor prognosis. We describe a case of salivary duct carcinoma arising in the hard palate of a 63-year-old man. Immunohistochemical analysis revealed that tumor cells tested positive for cytokeratin, epithelial membrane antigen, proliferating cell nuclear antigen, Ki67, p53, laminin, and collagen IV. Despite radical surgical resection, bilateral neck dissection, and postoperative radiotherapy, liver metastases developed, and the patient subsequently died of his disease.

引用

页码：689 / 692

页数：4

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