Age-related memory decline -: Current concepts and future directions

被引：118

作者：

Small, SA

机构：

[1] Columbia Univ Coll Phys & Surg, Div Neurobehav, New York, NY 10032 USA

[2] Columbia Univ Coll Phys & Surg, Taub Inst Res Alzheimers Dis & Aging Brain, New York, NY 10032 USA

来源：

ARCHIVES OF NEUROLOGY | 2001年 / 58卷 / 03期

关键词：

D O I：

10.1001/archneur.58.3.360

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The effect of age on memory and the brain has been the focus of many studies. Results have identified critical questions that need to be addressed to further our understanding of age-related memory decline: Is cognitive decline diffuse or selective? Where does memory decline localize to anatomically? Does decline represent an abnormal state? What are the causes of memory decline? What level of analysis is needed to investigate age-related cortical changes? These questions are reviewed herein, and attempts at early answers are discussed.

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页码：360 / 364

页数：5

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