Serological analysis of serum samples from humans exposed to Avian H7 influenza viruses in Italy between 1999 and 2003

被引:124
作者
Puzelli, S
Di Trani, L
Fabiani, C
Campitelli, L
De Marco, MA
Capua, I
Aguilera, JF
Zambon, M
Donatelli, I
机构
[1] Ist Super Sanita, Dept Infect Parasist & Immunomediated Dis, I-00161 Rome, Italy
[2] Ist Super Sanita, Dept Food & Anim Hlth, I-00161 Rome, Italy
[3] Ist Nazl Fauna Selvat, Bologna, Italy
[4] Ist Zooprofilatt Sperimentale Venezie, Padua, Italy
[5] Hlth Protect Agcy, Ctr Infect, London, England
关键词
D O I
10.1086/444390
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
We evaluated the potential for avian-to-human transmission of low pathogenic avian influenza (LPAI) and highly pathogenic avian influenza ( HPAI) H7N1 and LPAI H7N3 viruses that were responsible for several outbreaks of influenza in poultry in Italy between 1999 and 2003. A serological survey of poultry workers was conducted by use of a combination of methods. Evidence of anti-H7 antibodies was observed in 3.8% of serum samples collected from poultry workers during the period in 2003 when LPAI H7N3 virus was circulating. These findings highlight the need for surveillance in people occupationally exposed to avian influenza viruses, so that they can be monitored for the risk of avian-to-human transmission during outbreaks of avian influenza caused by both LPAI and HPAI viruses.
引用
收藏
页码:1318 / 1322
页数:5
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