Monodisperse, molecularly imprinted polymer microspheres prepared by precipitation polymerization for affinity separation applications

被引：331

作者：

Wang, JF

Cormack, PAG

Sherrington, DC

Khoshdel, E

机构：

[1] Univ Strathclyde, Dept Pure & Appl Chem, Glasgow G1 1XL, Lanark, Scotland

[2] Unilever Res Labs Vlaardingen, Wirral CH63 3JW, Merseyside, England

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2003年 / 42卷 / 43期

关键词：

imprinting; liquid chromatography; microporous solids; molecular recognition; polymerization;

D O I：

10.1002/anie.200352298

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Theophilline-imprinted polymer microspheres were obtained in monodisperse form with diameters of about 5 μm (see picture) in a single synthetic step by precipitation polymerization. This robust material, which proved suitable for use in HPLC, can, in principle, also be applied in any application in which molecular recognition phenomena play a role.

引用

页码：5336 / 5338

页数：3

共 31 条

[1] Molecular imprinting for drug bioanalysis - A review on the application of imprinted polymers to solid-phase extraction and binding assay [J].