Parental history of Type 2 diabetes in patients with nonaffective psychosis

被引：63

作者：

Femandez-Egea, Emilio ^{[2
]}

Miller, Brian ^{[1
]}

Bernardo, Miguel ^{[2
]}

Donner, Thomas ^{[3
]}

Kirkpatrick, Brian ^{[1
]}

机构：

[1] Med Coll Georgia, Dept Psychiat & Hlth Behav, Augusta, GA 30912 USA

[2] Univ Barcelona, Dept Psiquiatria, Inst Invest Biomed Agusti Pi & Sunyer,Hosp Clin, Programa Esquizofrenia Clin,Inst Neurociencies, Barcelona, Spain

[3] Univ Maryland, Dept Internal Med, Baltimore, MD 21201 USA

来源：

SCHIZOPHRENIA RESEARCH | 2008年 / 98卷 / 1-3期

关键词：

nonaffective psychosis; schizophrenia; type; 2; diabetes; family history; epidemiology;

D O I：

10.1016/j.schres.2007.10.002

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Introduction: We attempted to replicate two previous studies which found an increased risk of diabetes in the relatives of schizophrenia probands. Methods: N=34 patients with newly-diagnosed nonaffective psychosis and N=52 non-psychiatric controls were interviewed for parental history of Type 2 diabetes. Results: In a logistic regression model that included multiple potential confounders, psychosis was a significant predictor of Type 2 diabetes in either parent (p<0.04). Discussion: We found an increased prevalence of Type 2 diabetes in the parents of nonaffective psychosis subjects. This association may be due to shared environmental or genetic risk factors, or both. (C) 2007 Elsevier B.V. All rights reserved.

引用

页码：302 / 306

页数：5

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