Cannabis Use, Ischemic Stroke, and Multifocal Intracranial Vasoconstriction A Prospective Study in 48 Consecutive Young Patients

被引：134

作者：

Wolff, Valerie ^{[1
]}

Lauer, Valerie ^{[1
]}

Rouyer, Olivier ^{[2
]}

Sellal, Francois ^{[3
]}

Meyer, Nicolas ^{[4
]}

Raul, Jean Sebastien ^{[5
]}

Sabourdy, Cecile ^{[1
]}

Boujan, Fazel ^{[6
]}

Jahn, Christine ^{[6
]}

Beaujeux, Remy ^{[6
]}

Marescaux, Christian ^{[1
]}

机构：

[1] Hop Univ Strasbourg, Unite Neurovasc, Strasbourg, France

[2] Fac Med Strasbourg, EA 3072, Strasbourg, France

[3] Hop Colmar, Serv Neurol, Colmar, France

[4] HUS, Dept Biostat & Informat Med, Bordeaux, France

[5] HUS, Toxicol Lab, Inst Med Legale, Bordeaux, France

[6] HUS, Serv Radiol, Bordeaux, France

来源：

STROKE | 2011年 / 42卷 / 06期

关键词：

stroke in young adults; vasospasm; cannabis; CEREBROVASCULAR-DISEASE; MARIJUANA;

D O I：

10.1161/STROKEAHA.110.610915

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Background and Purpose-Our objective was to evaluate the relationship between cannabis use and ischemic stroke in a young adult population. Methods-Forty-eight consecutive young patients admitted for acute ischemic stroke participated in the study. First-line screening was performed, including blood tests, cardiovascular investigations, and urine analysis for cannabinoids. If no etiology was found, 3D rotational angiography and cerebrospinal fluid analysis were performed. A control was planned through neurovascular imaging within 3 to 6 months. Results-In this series, there was multifocal intracranial stenosis associated with cannabis use in 21% (n = 10). Conclusions-Multifocal angiopathy associated with cannabis consumption could be an important cause of ischemic stroke in young people. (Stroke. 2011; 42: 1778-1780.)

引用

页码：1778 / 1780

页数：3

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