OLAV-PMF: A novel scoring scheme for high-throughput peptide mass fingerprinting

被引：18

作者：

Magnin, J ^{[1
]}

Masselot, A ^{[1
]}

Menzel, C ^{[1
]}

Colinge, J ^{[1
]}

机构：

[1] Geneprot Inc, CH-1217 Meyrin, Switzerland

来源：

JOURNAL OF PROTEOME RESEARCH | 2004年 / 3卷 / 01期

关键词：

peptide mass fingerprint; protein identification; algorithm; scoring;

D O I：

10.1021/pr034055m

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

We propose anew type of probabilistic scoring scheme framework for protein identification from peptide masses. We first introduce the framework itself and explain its requirements. In a second part, we describe a particular implementation and test it on a data set of more than 8000 MALDI-TOF spectra with known contents. Doing so, we also compare its performance to two widely used scoring schemes, thereby demonstrating the potential of the proposed approach.

引用

页码：55 / 60

页数：6

共 24 条

[1] The SWISS-PROT protein sequence database and its supplement TrEMBL in 2000 [J].