High-contrast chemical imaging with gated heterodyne coherent anti-Stokes Raman scattering microscopy

被引：25

作者：

Greve, M

Bodermann, B

Telle, HR

Baum, P

Riedle, E

机构：

[1] Phys Tech Bundesanstalt, D-38116 Braunschweig, Germany

[2] Univ Munich, Lehrstuhl BioMol Opt, D-80538 Munich, Germany

来源：

APPLIED PHYSICS B-LASERS AND OPTICS | 2005年 / 81卷 / 07期

关键词：

D O I：

10.1007/s00340-005-1979-y

中图分类号：

O43 [光学];

学科分类号：

070207 [光学]; 0803 [光学工程];

摘要：

A novel method is presented which substantially improves the signal-to-background ratio for coherent anti-Stokes Raman scattering (CARS) microscopy. It exploits the fixed phase relation between pump, Stokes and CARS fields together with the strong phase coherence in supercontinua generated by femtosecond lasers. Three phase-locked optical parametric amplifiers are used for the realisation of heterodyne signal detection. Proper pulse timing yields a gating mechanism which nearly completely suppresses solvent background signals.

引用

收藏

页码：875 / 879

页数：5

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