Reversible deactivation of cerebral network components

被引:77
作者
Payne, BR
Lomber, SG
Villa, AE
Bullier, J
机构
[1] UNIV LAUSANNE,FAC MED,INST PHYSIOL,CH-1005 LAUSANNE,SWITZERLAND
[2] INSERM 371,F-69675 BRON,FRANCE
基金
美国国家卫生研究院;
关键词
D O I
10.1016/S0166-2236(96)10061-8
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Reversible deactivation techniques have shown that the cerebral network: (1) is dynamic, its functions depending on contemporaneous processing elsewhere in the network; (2) is composed of single nodes that contribute to several behaviors; (3) possesses an inherent plasticity that tends to minimize lesion-induced deficits; and (4) comprises feedforward and lateral connections that contribute in different ways to network operations. The next major advances in understanding network operations will probably be made by applying a combination of behavioral, neuron-recording and deactivation techniques. The greatest near-term gains ave likely to be made in understanding the contributions that feedback projections make to cerebral network function.
引用
收藏
页码:535 / 542
页数:8
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