Immunology of multiple sclerosis

被引:26
作者
Bar-Or, A
机构
[1] McGill Univ, Montreal Neurol Inst, Neuroimmunol Unit, Montreal, PQ H3A 2B4, Canada
[2] McGill Univ, Montreal, PQ, Canada
[3] McGill Univ Hosp Ctr, Montreal Neurol Hosp, Montreal, PQ, Canada
基金
加拿大健康研究院;
关键词
D O I
10.1016/j.ncl.2004.11.001
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
A model of multiple sclerosis (MS) immunopathophysiology is presented to illustrate the basic principles by which peripheral immune responses interact with the blood-brain barrier and have an impact on the central nervous system compartment. The model also considers the putative targets and modes of action of several MS therapies. Overall, this article should provide useful background for more detailed discussions of therapeutic strategies.
引用
收藏
页码:149 / +
页数:28
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