Static and kinetic studies on the adsorption behavior of sulfadiazene

To investigate the nature of interactive forces between sulfadiazene molecules and alumina surface the experiments were performed for the adsorption of sulfadiazene (SD) from its aqueous sulution onto the alumina surfaces at 25 +/- 0.2 degreesC and the influence of factors such as increasing concentration of SD (4.0-20.0 x 10(-3) mol cm(-3)), the time required for adsorption equilibrium, pH (2.0-12.0) and temperature (5-45 degreesC) of the adsorption medium, the presence of ions like Cl-, SO42- and PO43- (0.01-0.30 M) and organic solvents (5% v/v) were observed on the course of adsorption of SD. Various adsorption and kinetic parameters such as adsorption coefficient, the rate constants for adsorption and desorption were also evaluated. The results of the above cited studies facilitated to formulate the mechanisms of interaction between SD and alumina surfaces. From application view point the present work may be a potential tool for an effective chromatographic separation of sulfa drugs from industrial effluents.