Finite-size scaling of the quasispecies model

被引:40
作者
Campos, PRA [1 ]
Fontanari, JF [1 ]
机构
[1] Univ Sao Paulo, Inst Fis Sao Carlos, BR-13560970 Sao Carlos, SP, Brazil
来源
PHYSICAL REVIEW E | 1998年 / 58卷 / 02期
关键词
D O I
10.1103/PhysRevE.58.2664
中图分类号
O35 [流体力学]; O53 [等离子体物理学];
学科分类号
070204 ; 080103 ; 080704 ;
摘要
We use finite-size scaling to study the critical behavior of the quasispecies model of molecular evolution in the single-sharp-peak replication landscape. This model exhibits a sharp threshold phenomenon at Q=Q(c)= 1/a, where Q is the probability of exact replication of a molecule of length L, and a is the selective advantage of the master string. We investigate the sharpness of the threshold and find that its characteristics persist across a range of Q of order L-1 about Q(c). Furthermore, using the data collapsing method, we show that the normalized mean Hamming distance between the master string and the entire population, as well as the properly scaled fluctuations around this mean value, follow universal forms in the critical region.
引用
收藏
页码:2664 / 2667
页数:4
相关论文
共 10 条
[1]   Error threshold in finite populations [J].
Alves, D ;
Fontanari, JF .
PHYSICAL REVIEW E, 1998, 57 (06) :7008-7013
[2]  
Barber M. N., 1983, PHASE TRANSITIONS CR, V8
[4]   SELFORGANIZATION OF MATTER AND EVOLUTION OF BIOLOGICAL MACROMOLECULES [J].
EIGEN, M .
NATURWISSENSCHAFTEN, 1971, 58 (10) :465-+
[5]   Exact solution of the quasispecies model in a sharply peaked fitness landscape [J].
Galluccio, S .
PHYSICAL REVIEW E, 1997, 56 (04) :4526-4539
[6]   CRITICAL-BEHAVIOR IN THE SATISFIABILITY OF RANDOM BOOLEAN EXPRESSIONS [J].
KIRKPATRICK, S ;
SELMAN, B .
SCIENCE, 1994, 264 (5163) :1297-1301
[7]   STATISTICAL-MECHANICS OF EIGEN EVOLUTION MODEL [J].
LEUTHAUSSER, I .
JOURNAL OF STATISTICAL PHYSICS, 1987, 48 (1-2) :343-360
[8]   MODEL STUDIES ON RNA REPLICATION .2. SELF-REPLICATION WITH ERRORS - A MODEL FOR POLYNUCLEOTIDE REPLICATION [J].
SWETINA, J ;
SCHUSTER, P .
BIOPHYSICAL CHEMISTRY, 1982, 16 (04) :329-345
[9]   ERROR THRESHOLDS FOR MOLECULAR QUASI-SPECIES AS PHASE-TRANSITIONS - FROM SIMPLE LANDSCAPES TO SPIN-GLASS MODELS [J].
TARAZONA, P .
PHYSICAL REVIEW A, 1992, 45 (08) :6038-6050
[10]   Model dependency of error thresholds: the role of fitness functions and contrasts between the finite and infinite sites models [J].
Wiehe, T .
GENETICS RESEARCH, 1997, 69 (02) :127-136