Ion-selective lipid bilayers tethered to microcontact printed self-assembled monolayers containing cholesterol derivatives

被引：55

作者：

Jenkins, ATA ^{[1
]}

Bushby, RJ ^{[1
]}

Boden, N ^{[1
]}

Evans, SD ^{[1
]}

Knowles, PF ^{[1
]}

Liu, QY ^{[1
]}

Miles, RE ^{[1
]}

Ogier, SD ^{[1
]}

机构：

[1] Univ Leeds, Ctr Self Organising Mol Syst, Leeds LS2 9JT, W Yorkshire, England

来源：

LANGMUIR | 1998年 / 14卷 / 17期

关键词：

D O I：

10.1021/la980581u

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Microcontact printing has been used to prepare patterned self-assembled monolayers (SAMs) of cholesterylpolyethylenoxy thiol. These patterned SAMs were used as supports for the formation of integral supported lipid bilayers. Biofunctionality was confirmed by addition of valinomycin ionophores and gramicidin ion channels. Impedance spectroscopy of the resulting bilayer structures, incorporating valinomycin and the gramicidin, showed the expected ion selectivity.

引用

页码：4675 / 4678

页数：4

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