Effect of varicocelectomy on patients with unobstructive azoospermia and severe oligospermia

被引：39

作者：

Ishikawa, Tomomoto ^{[1
]}

Kondo, Yutaka ^{[1
]}

Yamaguchi, Kohei ^{[1
]}

Sakamoto, Yuichi ^{[1
]}

Fujisawa, Masato ^{[1
]}

机构：

[1] Kobe Univ, Grad Sch Med, Fac Med,Div Urol, Dept Organs Therapeut,Chuo Ku, Kobe, Hyogo 6500017, Japan

来源：

BJU INTERNATIONAL | 2008年 / 101卷 / 02期

关键词：

varicocele; ligation; azoospermia; severe oligospermia; spermatogenesis;

D O I：

10.1111/j.1464-410X.2007.07279.x

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 [临床医学]; 100201 [内科学];

摘要：

OBJECTIVES To assess the treatment outcome and benefits after varicocelectomy in men with unobstructive azoospermia (UOA) and severe oligospermia (SO). PATIENTS AND METHODS The records were retrospectively evaluated for six patients with UOA and 54 with SO who had microsurgical inguinal varicocele ligation (mean age 33.3 years, SD 5.3). Fifty-one (85%) had a unilateral left-sided procedure (five of six with UOA, 46 of 54 with SO), and nine (15%) had a bilateral procedure. RESULTS After ligation, spermatogenesis was induced in two of the six men with UOA; the mean (SD) sperm concentration increased from 2.3 (1.6) to 9.2 (12.6) million/mL (P < 0.001), but the sperm motility did not change significantly. Four (7%) of the 54 men with SO achieved paternity, with unassisted pregnancies. CONCLUSIONS Varicocelectomy resulted in the induction or enhancement of spermatogenesis for several men with UOA or SO; it seems to be a reasonable option in selected patients with UOA or SO.

引用

页码：216 / 218

页数：3

共 16 条

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[2]

A POSSIBLE ONTOGENIC ETIOLOGY FOR IDIOPATHIC LEFT VARICOCELE [J].