Roles of Na-K-2Cl and Na-Cl cotransporters and ROMK potassium channels in urinary concentrating mechanism

被引:52
作者
Hebert, SC [1 ]
机构
[1] Vanderbilt Univ, Div Nephrol, Nashville, TN 37232 USA
关键词
distal convoluted tubule; Bartter's syndrome; thick ascending limb of Henle;
D O I
10.1152/ajprenal.1998.275.3.F325
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
The cloning of the apical transport proteins involved in NaCl absorption in the thick ascending limb of Henle and the distal convoluted tubule has ushered in a new era that promises to provide molecular details of the urinary concentrating and diluting processes. We now have at hand tools to examine the regulation of these proteins that can affect the concentrating and diluting capacity.
引用
收藏
页码:F325 / F327
页数:3
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