TEQC: an R package for quality control in target capture experiments

被引：22

作者：

Hummel, Manuela ^{[1
]}

Bonnin, Sarah ^{[1
]}

Lowy, Ernesto ^{[1
]}

Roma, Guglielmo ^{[1
]}

机构：

[1] UPF, Core Facil, CRG, Barcelona, Spain

来源：

BIOINFORMATICS | 2011年 / 27卷 / 09期

关键词：

BIOCONDUCTOR; EXPLORATION;

D O I：

10.1093/bioinformatics/btr122

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

TEQC is an R/Bioconductor package for quality assessment of target enrichment experiments. Quality measures comprise specificity and sensitivity of the capture, enrichment, per-target read coverage and its relation to hybridization probe characteristics, coverage uniformity and reproducibility, and read duplicate analysis. Several diagnostic plots allow visual inspection of the data quality.

引用

页码：1316 / 1317

页数：2

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