Neuroimaging evidence for cortical involvement in the preparation and in the act of swallowing

被引:138
作者
Dziewas, R
Sörös, P
Ishii, R
Chau, W
Henningsen, H
Ringelstein, EB
Knecht, S
Pantev, C
机构
[1] Univ Toronto, Baycrest Ctr Geriatr Care, Rotman Res Inst, Toronto, ON M6A 2E1, Canada
[2] Univ Hosp Munster, Dept Neurol, D-48129 Munster, Germany
基金
加拿大健康研究院;
关键词
D O I
10.1016/S1053-8119(03)00285-4
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
This study employed whole head magnetoencephalography and synthetic aperture magnetometry to investigate the cortical topography of the preparation and the execution of volitional and reflexive water swallowing and of a simple tongue movement. Concerning movement execution, activation of the mid-lateral primary sensorimotor cortex was strongly lateralized to the left during volitional water swallowing, less strongly lateralized to the left during reflexive water swallowing, and not lateralized at all during tongue movement. In contrast, the preparation for both volitional water swallowing and tongue movement showed a bilateral activation of the primary sensorimotor cortex. No activation was seen prior to reflexive water swallowing. Activation of the left insula and frontal operculum was observed only during both the preparation and the execution of volitional water swallowing. These new findings suggest a left hemispheric dominance for the cortical control of swallowing in humans. (C) 2003 Elsevier Inc. All rights reserved.
引用
收藏
页码:135 / 144
页数:10
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