Neutrophil to Lymphocyte Ratio is Related to Stent Thrombosis and High Mortality in Patients With Acute Myocardial Infarction

被引:70
作者
Ayca, Burak [1 ]
Akin, Fatih [2 ]
Celik, Omer [3 ]
Sahin, Irfan [1 ]
Yildiz, S. Sezai [1 ]
Avci, I. Ilker [1 ]
Gulsen, Kamil [4 ]
Okuyan, Ertugrul [1 ]
Dinckal, M. Hakan [1 ]
机构
[1] Bagcilar Educ & Res Hosp, Dept Cardiol, Istanbul, Turkey
[2] Mugla Sitki Kocman Univ, Dept Cardiol, Mugla, Turkey
[3] Mehmet Akif Ersoy Chest & Cardiovasc Surg Educ &, Dept Cardiol, Istanbul, Turkey
[4] Near East Univ, Dept Cardiol, Mersin, Turkey
关键词
neutrophil to lymphocyte ratio; stent thrombosis; mortality; ST segment elevation myocardial infarction; PERCUTANEOUS CORONARY INTERVENTION; LONG-TERM MORTALITY; C-REACTIVE PROTEIN; ADVERSE CARDIAC EVENTS; ELUTING STENT; NEUTROPHIL/LYMPHOCYTE RATIO; ARTERY-DISEASE; TRIAL; COUNT; RISK;
D O I
10.1177/0003319714542997
中图分类号
R6 [外科学];
学科分类号
1002 ; 100210 ;
摘要
We investigated whether the neutrophil to lymphocyte ratio (NLR) can predict stent thrombosis (STh) and high mortality rate in patients with ST-segment elevation myocardial infarction (STEMI). We analyzed data of 102 patients with STh and 450 patients with STEMI admitted to 2 high volume hospitals. Preprocedural NLR was significantly higher in patients with STh (P < .001). There was a significantly higher mortality rate in patients with high NLR during hospitalization (P < .001). Also, in the STh group there was a significantly higher mortality rate in patients with high NLR (P < .001). In receiver-operating characteristic analysis, NLR >4.8 had 56% sensitivity and 68% specificity for predicting STh. The NLR >4.9 had 70% sensitivity and 65% specificity for predicting in-hospital mortality. On multivariate regression analysis, NLR was found to be significantly related to STh. In patients with STEMI, preprocedural high NLR is associated with both STh and higher mortality rates.
引用
收藏
页码:545 / 552
页数:8
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