Thyrsenols A and B, two unusual polyether squalene derivatives

被引：34

作者：

Norte, M ^{[1
]}

Fernandez, JJ ^{[1
]}

Souto, ML ^{[1
]}

Gavin, JA ^{[1
]}

GarciaGravalos, MD ^{[1
]}

机构：

[1] PHARMA MAR SA, MADRID 28760, SPAIN

来源：

TETRAHEDRON | 1997年 / 53卷 / 09期

关键词：

D O I：

10.1016/S0040-4020(97)00028-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Two new polyether squalene derivatives, thyrsenol A 2 and thyrsenol B 3, have been isolated from the red alga Laurencia viridis. Their structures, which possess all unusual enol-ether moiety were determined through the interpretation of 2D-NMR spectral data. The relative stereochemistry is proposed on the basis of ROESY and NOEDIFF data. Their cytotoxic activities were evaluated. (C) 1997 Published by Elsevier Science Ltd.

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页码：3173 / 3178

页数：6

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