COVID-19 and the Heart

被引：502

作者：

Akhmerov, Akbarshakh ^{[1
]}

Marban, Eduardo ^{[1
]}

机构：

[1] Cedars Sinai Med Ctr, Smidt Heart Inst, 127 S San Vicente Blvd,AHSP A3600, Los Angeles, CA 90048 USA

来源：

CIRCULATION RESEARCH | 2020年 / 126卷 / 10期

基金：

美国国家卫生研究院;

关键词：

biomarkers; cardiovascular diseases; coronavirus; inflammation; myocarditis; REGULATORY T-CELLS; ANGIOTENSIN-CONVERTING ENZYME-2; CARDIOSPHERE-DERIVED CELLS; CYTOKINE STORM; SARS; CORONAVIRUS; ACE2; IMPROVES; MODEL; LOPINAVIR/RITONAVIR;

D O I：

10.1161/CIRCRESAHA.120.317055

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Infection with the severe acute respiratory syndrome novel coronavirus produces a clinical syndrome known as 2019 novel coronavirus disease (COVID-19). When severe, COVID-19 is a systemic illness characterized by hyperinflammation, cytokine storm, and elevations of cardiac injury biomarkers. Here, we review what is known about the pathophysiology of COVID-19, its cardiovascular manifestations, and emerging therapeutic prospects. In this rapidly moving field, this review was comprehensive as of April 3, 2020.

引用

页码：1443 / 1455

页数：13

共 95 条

[1] Therapeutic efficacy of cardiosphere-derived cells in a transgenic mouse model of non-ischaemic dilated cardiomyopathy [J].

Aminzadeh, Mohammad A. ;

Tseliou, Eleni ;

Sun, Baiming ;

Cheng, Ke ;

Malliaras, Konstantinos ;

Makkar, Raj R. ;

Marban, Eduardo .

EUROPEAN HEART JOURNAL, 2015, 36 (12) :751-762

[2] Clinical Presentation and Outcome in a Contemporary Cohort of Patients With Acute Myocarditis: Multicenter Lombardy Registry [J].

Ammirati, Enrico ;

Cipriani, Manlio ;

Moro, Claudio ;

Raineri, Claudia ;

Pini, Daniela ;

Sormani, Paola ;

Mantovani, Riccardo ;

Varrenti, Marisa ;

Pedrotti, Patrizia ;

Conca, Cristina ;

Mafrici, Antonio ;

Grosu, Aurelia ;

Briguglia, Daniele ;

Guglielmetto, Silvia ;

Perego, Giovanni B. ;

Colombo, Stefania ;

Caico, Salvatore I. ;

Giannattasio, Cristina ;

Maestroni, Alberto ;

Carubelli, Valentina ;

Metra, Marco ;

Lombardi, Carlo ;

Campodonico, Jeness ;

Agostoni, Piergiuseppe ;

Peretto, Giovanni ;

Scelsi, Laura ;

Turco, Annalisa ;

Di Tano, Giuseppe ;

Campana, Carlo ;

Belloni, Armando ;

Morandi, Fabrizio ;

Mortara, Andrea ;

Ciro, Antonio ;

Senni, Michele ;

Gavazzi, Antonello ;

Frigerio, Maria ;

Oliva, Fabrizio ;

Camici, Paolo G. .

CIRCULATION, 2018, 138 (11) :1088-1099

[3]

[Anonymous], INTENS CARE MED 0311, DOI [DOI 10.1007/S15010-020-01424-5, DOI 10.1007/S15010-020-01473-W]

[4]

[Anonymous], COR DIS 2019 COVID 1

[5]

[Anonymous], JAMA CARDIOL

[6]

[Anonymous], N ENGL J MED

[7]

[Anonymous], N ENGL J MED

[8]

[Anonymous], EFFECTIVE TREATMENT

[9]

[Anonymous], EFFICACY HYDROXYCHLO, DOI 10.1101/2020.03.22.20040758

[10]

[Anonymous], N ENGL J MED

← 1 2 3 4 5 6 7 8 9 10 →