The human HLA-A*0201 allele, expressed in hamster cells, is not a high-affinity receptor for adenovirus type 5 fiber

被引：47

作者：

Davison, E

Kirby, I

Elliott, T

Santis, G

机构：

[1] Guys Hosp, Guys Kings Coll & St Thomas Hosp Sch Med, Dept Resp Med & Allergy, London SE1 9RT, England

[2] Univ Oxford, John Radcliffe Hosp, Nuffield Dept Clin Med, Immunochem Lab, Oxford OX3 9DU, England

来源：

JOURNAL OF VIROLOGY | 1999年 / 73卷 / 05期

基金：

英国惠康基金;

关键词：

D O I：

10.1128/JVI.73.5.4513-4517.1999

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The coxsackie B virus and adenovirus receptor (CAR) and the major histocompatibility complex (MHC) class I alpha 2 domain have been identified as high-affinity cell receptors for adenovirus type 5 (Ad5) fiber. In this study we show that CAR but not MHC class I allele HLA-A*0201 binds to Ad5 with high affinity when expressed on hamster cells. When both receptors are coexpressed on the cell surface of hamster cells, Ad5 fiber bind to a single high-affinity receptor, which is CAR.

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页码：4513 / 4517

页数：5

相关论文

共 17 条

[1] Isolation of a common receptor for coxsackie B viruses and adenoviruses 2 and 5 [J].

Bergelson, JM ;

Cunningham, JA ;

Droguett, G ;

KurtJones, EA ;

Krithivas, A ;

Hong, JS ;

Horwitz, MS ;

Crowell, RL ;

Finberg, RW .

SCIENCE, 1997, 275 (5304) :1320-1323

[2] The murine CAR homolog is a receptor for coxsackie B viruses and adenoviruses [J].

Bergelson, JM ;

Krithivas, A ;

Celi, L ;

Droguett, G ;

Horwitz, MS ;

Wickham, T ;

Crowell, RL ;

Finberg, RW .

JOURNAL OF VIROLOGY, 1998, 72 (01) :415-419

[3] HUMAN ADENOVIRUS-HOST CELL-INTERACTIONS - COMPARATIVE-STUDY WITH MEMBERS OF SUBGROUP-B AND SUBGROUP-C [J].

DEFER, C ;

BELIN, MT ;

CAILLETBOUDIN, ML ;

BOULANGER, P .

JOURNAL OF VIROLOGY, 1990, 64 (08) :3661-3673

[4] BIOCHEMICAL STUDY OF KB-CELL RECEPTOR FOR ADENOVIRUS [J].

HENNACHE, B ;

BOULANGER, P .

BIOCHEMICAL JOURNAL, 1977, 166 (02) :237-+

[5] CHARACTERIZATION OF THE KNOB DOMAIN OF THE ADENOVIRUS TYPE-5 FIBER PROTEIN EXPRESSED IN ESCHERICHIA-COLI [J].

HENRY, LJ ;

XIA, D ;

WILKE, ME ;

DEISENHOFER, J ;

GERARD, RD .

JOURNAL OF VIROLOGY, 1994, 68 (08) :5239-5246

[6] Adenovirus type 5 fiber knob binds to MHC class I alpha 2 domain at the surface of human epithelial and B lymphoblastoid cells [J].

Hong, SS ;

Karayan, L ;

Tournier, J ;

Curiel, DT ;

Boulanger, PA .

EMBO JOURNAL, 1997, 16 (09) :2294-2306

[7] A MONOCLONAL-ANTIBODY SPECIFIC FOR THE CELLULAR RECEPTOR FOR THE GROUP-B COXSACKIE-VIRUSES [J].

HSU, KHL ;

LONBERGHOLM, K ;

ALSTEIN, B ;

CROWELL, RL .

JOURNAL OF VIROLOGY, 1988, 62 (05) :1647-1652

[8] Structural and functional determinants in adenovirus type 2 penton base recombinant protein [J].

Karayan, L ;

Hong, SS ;

Gay, B ;

Tournier, J ;

DAngeac, AD ;

Boulanger, P .

JOURNAL OF VIROLOGY, 1997, 71 (11) :8678-8689

[9] PARTIAL-PURIFICATION AND SOME PROPERTIES OF BB7.2 - A CYTO-TOXIC MONOCLONAL-ANTIBODY WITH SPECIFICITY FOR HLA-A2 AND A VARIANT OF HLA-A28 [J].

PARHAM, P ;

BRODSKY, FM .

HUMAN IMMUNOLOGY, 1981, 3 (04) :277-299

[10] MONOCLONAL ANTIBODY TO A HUMAN HISTOCOMPATIBILITY ALLOANTIGEN, HLA-A2 [J].

PARHAM, P ;

BODMER, WF .

NATURE, 1978, 276 (5686) :397-399