The nuclear pore complex

被引:34
作者
Heese-Peck, A [1 ]
Raikhel, NV [1 ]
机构
[1] Michigan State Univ, US DOE, Plant Res Lab, E Lansing, MI 48824 USA
关键词
nuclear envelope; nuclear import; nuclear import receptor; nuclear pore complex; nucleoporin; O-linked GlcNAc modification;
D O I
10.1023/A:1006020204649
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The nuclear pore complex is the largest supramolecular complex that assembles in the eukaryotic cell. This structure is highly dynamic and must disassemble prior to mitosis and reassemble after the event. The directed movement of macromolecules into and out of the nucleus occurs through the nuclear pore complex, a potentially regulatory point for translocation. Using biochemical and genetic approaches, several nuclear pore complex proteins from yeast and vertebrates have been well characterized. Although very little is known about plant nuclear pore proteins, research is providing new information that indicates that plant nuclear pore complexes may have some unique features.
引用
收藏
页码:145 / 162
页数:18
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